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I Think this answers my question posted on CameraQuest.com
THE DISADVANTAGE is inconvenience. There is no linkage between the EOS body and the adapted lens. You will have manual focus only. You will manually control the lens aperture. For example, if you set the lens aperture ring at f/11, the lens aperture is indeed at f/11. IF you want the lens to be wide open, you manually open it by turning the lens aperture.
If you are shooting video, many people view this as an advantage, not a disadvantage...
I have a Nikkor ED 50-300 and it's all manual. I just have a hard time getting used to it when I do use it. (kind wierd bolting the lens to the tripod and then letting the camera dangle off the lens.)