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The sharpness & coring settings can't be fixed or undone much in post, although you can very effectively sharpen in post.
Also the knee setting affecting the retention of highlights can't be duplicated in post. I.E. you won't get highlights back in post.
Most everything else can be addressed in post. But it's always easier the closer you are to the look you want natively.
Plus like Denwa said, tweaking for noise reduction is key.