Samuel H
Major Contributor
Yes, bigger sensors make sharper pictures, in general. And even more so if you compare at constant DoF (closing more the aperture on the bigger sensor).
And since we're talking about ludicrously expensive gear... the OTUS was spectacular when it came out, but it has competition nowadays, at least if you only care about sharpness. In real world tests, the Sigma 28mm f/1.4 Art slightly beats the OTUS 28mm f/1.4, and the Sigma 40mm f/1.4 Art slightly beats the OTUS 55mm (link). And in theoretical MTF, the new Sigma 85mm f/1.4 designed specifically for mirrorless slightly beats the OTUS 85mm f/1.4 (link), at $1200 vs $4500 and 625g vs 1140g.
None of these could come close to those Fuji medium format figures, though, especially if you consider that you'd have to compare the MTF 40 of the FF lens with the MTF 30 of the MF lens (it's a 1.3x bigger sensor).
And since we're talking about ludicrously expensive gear... the OTUS was spectacular when it came out, but it has competition nowadays, at least if you only care about sharpness. In real world tests, the Sigma 28mm f/1.4 Art slightly beats the OTUS 28mm f/1.4, and the Sigma 40mm f/1.4 Art slightly beats the OTUS 55mm (link). And in theoretical MTF, the new Sigma 85mm f/1.4 designed specifically for mirrorless slightly beats the OTUS 85mm f/1.4 (link), at $1200 vs $4500 and 625g vs 1140g.
None of these could come close to those Fuji medium format figures, though, especially if you consider that you'd have to compare the MTF 40 of the FF lens with the MTF 30 of the MF lens (it's a 1.3x bigger sensor).