Do you or does Amazon have ads running every few minutes or at the opening?
YouTube will vary, depending upon a channel. Some use pop-ups, some hard ads. IMO, super-short (5 seconds and under ads) are feasible but, just from being a viewer, I know I will often skip a video entirely if I have to watch a 15-sec ad that I have no interest in. Daily Motion will frequently run a 30-sec ad every 5 minutes and, likewise, I will often close the window rather than watch the ad.
I have prime and ads enabled. Out of the 55,000 views only 330 of them were played with ads, all the rest through prime membership.